Publications

Google Scholar Link

PubMed Link

 

2017

  • AC Anselmo, B Prabhakarpandian, K Pant, and S Mitragotri, "Clinical and commercial translation of advanced polymeric nanoparticle systems: opportunities and material challenges", Translational Materials Research, 4(1): 014001.
  • J Niu, DJ Lunn, A Pusuluri, JI Yoo, MA O'Malley, S Mitragotri, HT Soh, and CJ Hawker, "Engineering live cell surfaces with functional polymers via cytocompatible controlled radical polymerization", Nature Chemistry, doi: 10.1038/nchem2713.
  • S Mitragotri, T Lammers, Y Han Bae, S Schwendeman, S De Smedt, et al., "Drug Delivery Research for the Future: Expanding the Nanno Horizons and Beyond", Journal of Controlled Release, 246: 183-184. 
  • AC Anselmo and S Mitragotri, "Impact of Particle Elasticity on Particle-Based Drug Delivery Systems", Advanced Drug Delivery Reviews, 108: 51-67.

2016

  • P Decuzzi, S Mitragotri, "Introduction to special issue on "Nanoparticles in Medicine: Targeting, Optimization and Clinical Applications"", Bioengineering & Translational Medicine, 1(1): 5-7.
  • M Zakrewski, S Mitragotri, "Theraputic RNAi robed with ionic liquid moieties as a simple, scalable prodrug platform for treating skin disease", Journal of Controlled Release, 242: 80-88.
  • R Rotstein, A Berges, S Mitragotri, DE Morse, M Moskovits, "Angle-dependent light scattering by highly uniform colloidal rod-shaped microparticles: Experiment and simulation", Journal of Polymer Science Part B: Polymer Physics, 54(18): 1889-1895.
  • C Villa, AC Anselmo, S Mitragotri, and V Muzykantov, "Red blood cells: Supercarriers for drugs, biologicals, and nanoparticles and inspiration for advanced delivery systems", Advanced Drug Delivery Reviews, 106 (Part A): 88-103.
  • A Banerjee, JH Lee, and S Mitragotri, "Intestinal Mucoadhesive Devices for Oral Delivery of Insulin”, Bioengineering & Translational Medicine, 1(3): 338-346. 
  • AC Anselmo and S Mitragotri, "Nanoparticles in the clinic", Bioengineering & Translational Medicine, 1(1): 10-29.
  • A Banerjee, J Qi, R Gogoi, J Wong, and S Mitragotri, "Role of nanoparticle size, shape and surface chemistry in oral drug delivery", Journal of Controlled Release, 238, 176-185.
  • KM Camacho, S Menegatti, D Vogus, A Pusluri, Z Fuchs, M Jarvis, M Zakrewsky, M Evans, and S Mitragotri, "DAFODIL: A novel liposome-encapsulated synergistic combination of doxorubicin and 5FU for low dose chemotherapy", Journal of Controlled Release, 229, 154-162.
  • M Zakrewsky, A Banerjee, S Apte, T Kern, MR Jones, RE Del Sesto, A Kopposch, DT Fox, and S Mitragotri, "Choline and geranate deep eutectic solvent as a Broad-Spectrum Antiseptic Agent for Preventive and Therapeutic Applications", Advanced Healthcare Materials, 5(11), 1282-1289.
  • J Myserson, AC Anselmo, Y Liu, S Mitragotri, D Eckmann, and V Muzykantov, "Non-affinity factors modulating vascular targeting of nano- and microcarriers", Advanced Drug Delivery Reviews, 99(PartA), 97-112.
  • AC Anselmo, and S Mitragotri, "A Chemical Engineering Perspective of Nanoparticle-based Targeted Drug Delivery: A Unit Process Approach", AIChE., 62(4), 966-974.
  • V Gupta, BH Hwang, N Doshi, A Banerjee, AC Anselmo, and S Mitragotri, "Delivery of Exenatide and Insulin Using Mucoadhesive Intestinal Devices", Annals of Biomedical Eng., Annals of Biomedical Engineering, 44(6), 1993-2007.
  • M Zakrewsky, JA Muraski, and S Mitragotri, "Mechanistic Analysis of Cellular Internalization of a Cell-and Skin-Penetrating Peptide", Regenerative Engineering and Translational Medicine, 2(1), 23-26.
  • KM Camacho, S Menegatti, and S Mitragotri, "Low-molecular-weight-Polymer-drug Conjugates for Synergistic Anticancer Activity of Camptothecin and Doxorubicin Combinations", Nanomedicine, 11(9), 1139-1151.
  • D Pan, O Vargas-Morales, B. Zern, AC Anselmo, V Gupta, M Zakrewsky, S Mitragotri, V Muzykantov, "The Effect of Polymeric Nanoparticles on Biocompatibility of Carrier Red Blood Cells", PloS one,11(3), e0152074.
  • S Menegatti, M Zakrewsky, S Kumar, J Oliveira, JA Muraski, and S Mitragotri, "De novo Design of Skin-penetrating Peptides for Enhanced Transdermal Delivery of Peptide Drugs”, Advanced Healthcare Materials, 5(5), 602-609.

2015

  • K Aoyagi, M Zakrewsky, and S Mitragotri, "Formulating propranolol as an amorphous melt affords reduced skin irritation potential for transdermal drug delivery", Technology, 3(4), 214-238.
  • S Mitragotri and J Hanes, "Journal of Drug Delivery Life Time Achievement Award for Prof. Robert Lager”, Journal of Drug Targeting, 23(7-8): 579.
  • JW Myerson, AC Anselmo, Y Liu, S Mitragotri, D Eckmann, and V Muzykantov, "Non-affinity factors modulating vascular targeting of nano- and microcarriers", Advanced Drug Delivery ReviewsS0169-409X(15)00236-7.
  • S Kumar, AC Anselmo, A Banerjee, and S Mitragotri, "Shape and size-dependent immune response to antigen-carrying nanoparticles", J Control Rel., 220 (Pt A), 141-148. 
  • M Zakrewsky, S Kumar, and S Mitragotri, “Nucleic acid delivery into skin for the treatment of skin disease: Proofs-of-concept, potential impact, and remaining challenges”, J Control Rel., 219, 445-456.
  • K Aoyagi, M Zakrewsky, and S Mitragotri, "Formulating propranolol as an amorphous melt affords reduced skin irritation potential for transdermal drug delivery”, Technology, 3 (04), 1550010. 
  • S Menegatti, N Ruocco, S Kumar, M Zakrewsky, J Oliveira, ME Helgeson, LG Leal, and S Mitragotri, “Synthesis and characterization of a self-fluorescent hyaluronic acid-based gel for Dermal applications”, Advanced Healthcare Materials, 4(15):2297-2305.
  • S Mitragotri, DG Anderson, X Chen, EK Chow, D Ho, AV Kabanov, JM Karp, K Kataoka, CA Mirkin, SH Petrosko, J Shi, MM Stevens, S Sun, S Teoh, SS Venkatraman, Y Xia, S Wang, Z Gu, and C Xu, "Accelerating the Translation of Nanomaterials in Biomedicine”,  ACS Nano, 9(7):6644-54.
  • AC Anselmo, S Kumar, V Gupta, AM Pearce, A Ragusa, V Muzykantov, and S Mitragotri, "Exploiting Shape, Cellular-Hitchhiking and Antibodies to Target Nanoparticles to Lung Endothelium: Synergy Between Physical, Chemical and Biological Approaches”, Biomaterials, 68, 1-8. 
  • D Paithankar, BH Hwang, G Munavalli, A Kauvar, J Lloyd, R Blomgren et al., “Ultrasonic delivery of silica–gold nanoshells for photothermolysis of sebaceous glands in humans: Nanotechnology from the bench to clinic”, Journal of Controlled Release, 206, 30-36.
  • AC Anselmo and S Mitragotri, “A Review of Clinical Translation of Inorganic Nanoparticles”, AAPS Journal, 17(5):1041-54.
  • S Kumar, M Chen, AC Anselmo, JA Muraski, and S Mitragotri, “Enhanced epidermal localization of topically applied steroids using SPACE™ peptide”, Drug delivery and translational research, 5(5):523-30.

  • KM Camacho, S Kumar, S Menegatti, DR Vogus, AC Anselmo, and S Mitragotri, “Synergistic Antitumor Activity of Camptothecin-Doxorubicin Combinations and their Conjugates with Hyaluronic Acid”, Journal of Controlled Release, 210, 198-207.

  • AC Anselmo, M Zhang, S Kumar, DR Vogus, S Menegatti, ME Helgeson et al., “Elasticity of Nanoparticles Influences Their Blood Circulation, Phagocytosis, Endocytosis and Targeting”, ACS Nano 9(3):3169-77.
  • S Kumar, M Zakrewsky, M Chen, S Menegatti, JA Muraski, and S Mitragotri, “Peptides as skin penetration enhancers: Mechanisms of action”, Journal of Controlled Release, 199, 168-178.
  • AC Anselmo, JB Gilbert, S Kumar, V Gupta, RE Cohen, MF Rubner et al. “Monocyte-mediated delivery of polymeric backpacks to inflamed tissues: a generalized strategy to deliver drugs to treat inflammation”, Journal of Controlled Release, 199, 29-36.
  • M Chen, S Kumar, AC Anselmo, V Gupta, DH Slee, JA Muraski et al. “Topical delivery of Cyclosporine A into the skin using SPACE-peptide”, Journal of Controlled Release, 199, 190-197.
  • A Anselmo and S Mitragotri, "Biomimetic Engineering of Particles: Synthetic Cells", Indian CRS Newsletter.

2014

  • AC Anselmo, CL Modery-Pawlowski, S Menegatti, S Kumar, DR Vogus et al. “Platelet-like Nanoparticles: Mimicking Shape, Flexibility, and Surface Biology of Platelets To Target Vascular Injuries”, ACS Nano, 8 (11), 11243-11253.
  • NA Peppas, R Duncan, GE Wnek, AS Hoffman, GH Gao, SW Kim, DS Lee et al. “Highly cited research articles in Journal of Controlled Release: Commentaries and perspectives by authors”, Journal of Controlled Release, 190, 29-74.
  • AC Anselmo and S Mitragotri. “Cell-mediated delivery of nanoparticles: Taking advantage of circulatory cells to target nanoparticles”, Journal of Controlled Release, 190, 531-541.
  • AC Anselmo and S Mitragotri, “An overview of clinical and commercial impact of drug delivery systems”, Journal of Controlled Release, 190, 15-28.
  • M Zakrewsky, KS Lovejoy, TL Kern, TE Miller, V Le, A Nagy, AM Goumas et al., “Ionic liquids as a class of materials for transdermal delivery and pathogen neutralization”, Proceedings of the National Academy of Sciences, 111 (37), 13313-13318.
  • S Mitragotri, PA Burke, and R Langer, “Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies”, Nature Reviews Drug Discovery, 13 (9), 655-672.
  • M Howard, BJ Zern, AC Anselmo, VV Shuvaev, and S Mitragotri, “Vascular targeting of nanocarriers: Perplexing aspects of the seemingly straightforward paradigm”, ACS Nano, 8 (5), 4100-4132.
  • D Sarkar, W Liu, X Xie, AC Anselmo, S Mitragotri, and K Banerjee, “Correction to MoS2 Field-Effect Transistor for Next-Generation Label-Free Biosensors”, ACS Nano, 8 (5), 5367-5367     .
  • R Rotstein, S Mitragotri, M Moskovits, and DE Morse, “Progressive transition from resonant to diffuse reflection in anisotropic colloidal films”, Journal of Polymer Science Part B: Polymer Physics, 52 (9), 611-617.
  • S Barua and S Mitragotri, “Challenges associated with penetration of nanoparticles across cell and tissue barriers: A review of current status and future prospects”, Nano Today, 9 (2), 223-243.
  • M Chen, M Zakrewsky, V Gupta, AC Anselmo, DH Slee, JA Muraski et al., “Topical delivery of siRNA into skin using SPACE-peptide carriers”, Journal of Controlled Release, 179, 33-41.
  • D Sarkar, W Liu, X Xie, AC Anselmo, S Mitragotri, and K Banerjee, “MoS2 field-effect transistor for next-generation label-free biosensors”, ACS Nano, 8 (4), 3992-4003.
  • G Munavalli, J Lloyd, R Blomgren, A Kauvar, T Meyer, L Faupel, et al., “Selective Photothermolysis of Sebaceous Glands for Treatment of Acne: Efficient Delivery of Gold Coated Microparticles as Chromophores into the Sebaceous Glands with Ultrasound, A Human Histology Study”, Lasers in Surgery and Medicine, 46, 3-4.
  • BH Hwang, S Mitragotri, V Pattani, J Tunnell, R Blomgren, T Meyer, et al., “Selective Photothermolysis of Sebaceous Glands via Efficient Delivery of Gold Coated Microparticles into the Glands with Ultrasound, An Ex Vivo Optimization Study”, Lasers in Surgery and Medicine, 46, 34-35.
  • S Mitragotri and P Stayton, “Organic nanoparticles for drug delivery and imaging”, MRS Bulletin, 39 (03), 219-223.
  • M Chen, V Gupta, AC Anselmo, JA Muraski, and S Mitragotri, “Topical delivery of hyaluronic acid into skin using SPACE-peptide carriers”, Journal of Controlled Release, 173, 67-74.

2013

  • Paliwal, S., Hwang, B.H., Tsai, K.Y., Mitragotri, S., "Diagnostic Opportunities Based on Skin Biomarkers", European Journal of Pharmaceutical Sciences, 50(5), 546-556.
  • Anselmo, A.C., Gupta, V., Zern, B., Pan, D., Zakrewsky, M., Muzykantov, V., and Mitragotri, S., “Delivering Nanoparticles to Lungs While Avoiding Liver and Spleen through Adsorption on Red Blood Cells”, ACS Nano, 7(12), 11129-11137.
  • Gupta, V., Hwang, B., Lee, J., Anselmo, A., Doshi, N., and Mitragotri, S., “Mucoadhesive Intestinal Devices for Oral Delivery of Salmon Calcitonin”, J. Control. Rel., 172(3), 753-762.
  • Barua, S. and Mitragotri, S., “Synergistic Targeting of Cell Membrane, Nucleus and Cytoplasm using Shape-Engineered Nanoparticles”, ACS Nano, 7(11), 9558-9570.
  • Gupta, V., Doshi, N., and Mitragotri, S., “Permeation of insulin, calcitonin and exenatide across Caco-2 monolayers: measurement using a rapid, 3-day system”, PLOSone, 8(2), e57136.
  • Mitragotri, S., "Devices for overcoming biological barriers: The use of physical forces to disrupt the barriers, Adv Drug Deliv Rev., 65(1), 100-3.
  • Modery-Pawlowski, C., Tian, L., Pan, V., McCrae, K., Mitragotri, S., and Sen Gupta, A., "Approaches to synthetic platelet analogs", Biomaterials, 34(2), 526-41.
  • Gupta, V., Hwang, B.H., Doshi, N., and Mitragotri, S., “A Permeation Enhancer for Oral Delivery of Therapeutic Macromolecules”, J. Control. Rel., 172(2), 541-549.
  • Kolhar, P., Anselmo, A., Gupta, V., Prabhakarpandian, B., Pant, K., Ruoslahti, R., and Mitragotri, S., “Using Shape Effects to Target Nanoparticles to Lung and Brain Endothelium”, PNAS, 110(26), 10753-8.
  • Mitragotri, S., “Engineering Contributions to Transdermal Drug Delivery: A Tribute to Contributions of Robert Langer”, Skin Phyiol. Pharmacol., 26(4-6), 263-76.
  • Barua, S., Yoo, J.-W. , Kolhar, P., Wakankar, A., Gokarn, Y., and Mitragotri, S., “Particle Shape Enhances Avidity and Specificity of Antibodies”, PNAS, 110(9), 3270-5.
  • Bao, G., Mitragotri, S., and Tong, S., “Multi-functional Nanoparticles for Drug Delivery for Drug Delivery and Molecular Imaging”, Ann. Rev. Biomed Eng., 15, 253-82.
  • Zhou, Z., Anselmo, A., and Mitragotri, S., “Fabrication of protein-based rod-shaped particles from spherical templates using layer-by-layer assembly”, Advanced Materials, 25(19), 2723-7.
  • Mitragotri, S., “Low-Frequency Sonophoresis”, In Perspectives in Percutaneous Absorption, Ed. Maibach H.
  • Hwang, B., Tsai, K.Y., and Mitragotri, S., “Optimized lysis buffer reagents for solubilization and preservation of proteins from cells and tissues”, Drug Del. Tans. Res., 3, 428-436.

2012

  • Pino, C., Gutterman, J.U., Vonwil, D., Mitragotri, S., and Shastri, V.P., “Glycosylation Facilitates Transdermal Transport of Macromolecules”, PNAS, 109(52):21283-8, 2012.
  • Mitragotri, S., “Mechanical Disruption of Skin for Vaccine Delivery”, J. Drug Delivery Systems, 27(3), 202-212.
  • Mitragotri, S. and Lahann, J., “Material Designs for Overcoming Biological Hurdles in Drug Delivery”, Advanced Materials, 24(28):3717-23.
  • Doshi, N., Orje, J., Smith, J.W., Mitragotri, S., and Ruggeri, Z.M., "Platelet Mimetic Particles for Targeted Drug Delivery", Advanced Materials, 24(28):3864-9.
  • Hwang, B., Doshi, N., Tsai, K., and Mitragotri, S., “A Regent to Recover Proteins from Cells and Tissues”, Drug Delivery and Translational Research, 2(5), 297-304.
  • Masaeli, M., Sollier, E., Amini, H., Mao, W., Camacho, K., Mitragotri, S., Alexeev, A., and Di Carlo, D., "Shape-based Separation by Inertial Focusing", Phys. Rev. X, 2(3), 031017.
  • Lee, K.J., Yoon, J., Rahmani, S., Hwang, S., Bhaskar, S., Mitragotri, S., and Lahann, L., "Shape Reconfiguring Microcylinders", PNAS, 109(40), 16057-62.
  • Kolhar, P. and Mitragotri, S., “Size and Shape of Microparticles Impact their Localization around the Nucleus after Endocytosis”, Advanced Functional Materials, 28(12), 3759–3764.
  • Pangarkar, C., Dinh, A.T., and Mitragotri, S., “Endocytic Pathway is Naturally Tuned to Rapidly Deliver Drugs to Lysosomes”, J. Control. Rel., 162(1), 76-83.
  • Kirsch, J., Doshi, N., Mitragotri, S., and Lehr, C.M., “Mucociliary Clearance of Nanoparticles - the Role of Fluid Dynamics at the Nanoscale”, Journal of Controlled Release, 159(1), 128-34.
  • Ogura, M., Paliwal, S., and Mitragotri, S., “Sampling of Disease Biomarkers from Skin for Theranostic Applications”, Drug Delivery and Translational Research, 2(2), 87-94.

2011

  • Yoo, J.-W. and Mitragotri, S., “Designing Micro- and Nanoparticles for Treating Rheumatoid Arthritis”, Arch.Dermatol. Res., 34(11), 1887-1897.
  • Doshi, N., Swiston, A., Cohen, R., Rubner, M., and Mitragotri, S., “Cell-based Drug Delivery Systems using Backpacks”, Adv. Materials, 23(12), H105-9.
  • Mitragotri, S., Anissimov, Y., Bunge, A., Frasch, F., Guy R., Kasting, G., Lane, M., and Roberts, M., “Mathematical Models of Skin Permeability: An Overview”, Int. J. Pharm., 418(1), 115-29.
  • Mitragotri, S. and Vanbever, R., “Converting Innovative Colloids into Potent Drug Carriers: Opportunities and Challenges”, Current Opinion in Colloids and Interface and Science, 16(3), 169-170.
  • Kolhar, P., Doshi, N., and Mitragotri, S., “Polymer Nano-needles for Intracellular Drug Delivery”, Small, 7(14), 2094-100.
  • Yoo, J.W., Doshi, N., and Mitragotri, S., “Adaptive Strategies for Drug Delivery”, Advanced Drug Delivery Reviews, 63(14-15), 1247-56.
  • Yoo, J.W., Irvine, D., Discher, D.E., and Mitragotri, S., “Bio-inspired, Bio-mimetic, and Bio-engineered Systems for Drug Delivery”, Nature Reviews Drug Discovery, 10(7), 521-35.
  • Hsu, T. and Mitragotri, S., “Discovery of Peptide Chaperones for Delivery of siRNA and other Macromolecules into Skin”, PNAS, 108(38), 15816-21.
  • Sharma, G., Valenta, D., Altman, Y., Harvey, S., Xie, H., Mitragotri, S., and Smith, J.W., “Polymer particle shape independently influences binding and internalization by macrophages”, J. Control. Rel.147(3), 408-12.
  • Michinaka, Y. and Mitragotri, S., “Delivery of Polymeric Particles into Skin using Needle-free Liquid Jet injectors”, J. Control Rel., 153(3), 249-54.

2010

  • Paliwal, S., Ogura, M., and Mitragotri, S., “One-Step Sampling of Biomolecules from Skin” PNAS, 107(33), 14627-32.
  • Yoo, J.-W., Chambers, E., and Mitragotri, S., “Factors that Influence Circulation of Nanoparticles in Blood”,Curr. Pharm. Des. , 16(21), 2298-301.
  • Yoo, J.-W. and Mitragotri, S., “Polymer Particles that Switch Shape in Response to a Stimulus”, PNAS, 107(25), 11205-10.
  • Champion, J.A. and Mitragotri, S., “UFOs, Worms and Surfboards: What Roles Teach us about Cell-Material Interactions”, Advances in Regenerative Medicine: Role of Nanotechnology and Engineering Principles, 301-323.
  • Doshi, N. and Mitragotri, S., “Needle-shape Polymer Particles Induce Transient Disruption of Cell Membranes”, J. Roy. Soc. Int., 7 (supp 4), S403-10.
  • Doshi, N. and Mitragotri, S., “Macrophages Recognize Size and Shape of their Targets”, PLoSOne, 5(4), e10051.
  • James-Smith, M.A., Hellner, B., Annunziato, N., and Mitragotri, S., “Effect of Surfactant Mixtures on Skin Structure and Barrier Properties”Annal. Biomed. Eng.,39(4), 1215–1223.
  • Doshi, N., Prabhakarpandian, B., Rea-Ramsey, A., Sundaram, S., Pant, K., and Mitragotri, S., “Flow and Adhesion of Sphere, Rod and Disk-shaped Particles in Blood Vessels: A Study using Model Synthetic Microvascular Networks”, J. Control. Rel., 146(2), 196-200.
  • Karande, P. and Mitragotri, S., “Transcutaneous Immunization: A Review of Principles, Methods and Applications”, Ann. Rev. Biochem. Eng., vol. 1, 175-201.
  • Paliwal, S., Ogura, M., and Mitragotri, S., “Rapid Sampling of Molecules from the Skin for Diagnostic and Forensic Applications", Pharm. Res., 27(7), 1255-63.
  • Arora, A. and Mitragotri, S., “Novel Topical Microbicides by Combinatorial Approaches”, Pharm. Res., 27(7), 1264-72.
  • Arora, A., Kisak, E., Karande, P., Newsam, J., and Mitragotri, S., “Design of Multicomponent Formulations for Transdermal Delivery: More is not Always Better”, J. Control. Rel., 144(2), 175-80.
  • Doshi, N. and Mitragotri, S., “Designer Biomaterials for Nanotechnology”, Adv. Functional Mater.,19(24), 3843-3854.
  • Yoo, J.-W., Doshi, N., and Mitragotri S., “Endocytosis and Intracellular Distribution of PLGA Particles in Endothelial Cells: Effect of Particle Geometry” Macromol. Rapid Comm., 31(2), 142-148.
  • Liu, Y., Paliwal, S., Bankiewicz, K.S., Bringas, J.R., Heart G., Mitragotri, S., and Prausnitz, M.R., “Ultrasound-assisted drug delivery in the brain”, AAPS Pharm Sci., 11(3), 1005-1017.

2009

  • Doshi, N., Zahr, A., Bhaskar, S., Lahann, J., and Mitragotri, S., “Red Blood Cell Mimicking Synthetic Biomaterial Particles”, PNAS, 106, 21495-9.
  • Karande, P. and Mitragotri, S., “Synergistic Effects of Chemical Penetration Enhancers on Skin Permeability”, BiochimBiophys. Acta, 1788(11), 2362-73.
  • Mitragotri, S., “In Drug Delivery, Shape Does Matter”, Pharm. Res., 26(1), 232-4.
  • Mitragotri, S., “Needle-free Methods of Drug Delivery”, The Bridge, 38(2), 5-12.
  • Champion, J.A. and Mitragotri, S., “Shape-induced Inhibition of Phagocytosis of Polymer Particles”, Pharm. Res., 26(1), 244-9.
  • Stachowiak, J.C., Li, T.H., Arora, A., Mitragotri, S., and Fletcher, D.A., “Dynamic Control of a Needle-free Jet Injector for Transdermal Drug Delivery”, J. Control. Rel., 135(2), 104-12.
  • Mitragotri, S. and Lahann, J., “Designer Biomaterials: Physical Answers to Biological Questions”, Nature Materials, 8(1), 15-23.
  • Karande, P., Arora, A., Pham, T.K., Stevens, D., Wojicki, A., and Mitragotri, S., “Transcutaneous Immunization using Common Chemicals”, J. Control. Rel., 138(2), 134-40.

2008

  • Muro, S., Garnacho, C., Champion, J.A., Leferovich, J., Gajewski, C., Schuchman, E.H., Mitragotri,S., and Muzykantov, V.R., “Controlled endothelial targeting and sub-cellular delivery of therapeutics by modulating size and shape of ICAM-1-targeted carriers”, Mol. Ther., 16(8), 1450-8.
  • Arora, A., Prausnitz, M.R., and Mitragotri, S., “Micro-scale Devices for Transdermal Drug Delivery”, Int. J. Pharm. 364(2), 227-36.
  • Whitehead, K. and Mitragotri, S., “Mechanisms Analysis of Chemical Permeation Enhancers for Oral Drug Delivery”, Pharm. Res., 25(6), 1412-9.
  • Whitehead, K., Karr, N., and Mitragotri, S., “Discovery of synergistic permeation enhancers for oral drug delivery”, J. Control Release, 128(2), 128-33.
  • Dinh, T., Pangarkar, C. and Mitragotri, S., “Discrete Nanoscale Transport in Biological Systems: Opportunities for Chemical Engineers”,Chemical Engineering Progress, 104(6).
  • Ogura, M., Paliwal, S., and Mitragotri, S., “Low-Frequency Sonophoresis” Advanced Drug Delivery Reviews, 60(10), 1218-23.
  • Paliwal, S. and Mitragotri S., "Therapeutic Opportunities in Biological Responses of Ultrasound," Ultrasonics, 48(4), 271-8.
  • Whitehead, K. and Mitragotri, S., “Safe and Effective Permeation Enhancers for Oral Drug Delivery”, Pharm. Res., 25(8), 1782-8.
  • Champion, J.A., Walker, A., and Mitragotri, S., "Recognition of Particle Size by Macrophages during Phagocytosis," Pharm. Res., 25(8), 1815-1821.

2007

  • Hall, S.S., Mitragotri, S., and Daugherty, P., "Identification of peptide ligands facilitating nanoparticle attachment to erythrocytes," BiotechnolProg., 23(3), 749-54.
  • Champion, J.A., Katare, Y., and Mitragotri, S., "Particle shape: a new design parameter for micro- and nanoscale drug delivery carriers," J Control Release, 121(1-2), 3-9.
  • Champion, J.A., Katare, Y., and Mitragotri, S., "Making polymeric micro- and nanoparticles of complex shapes," PNAS. 104(29), 11901-4.
  • Mitragotri, S., "Temperature-Dependence of Skin Permeability to Hydrophilic and Hydrophobic Solutes”, J. Pharm. Sci, 96(7), 1832-9.
  • Chambers, E. and Mitragotri, S., "Long circulating nanoparticles via adhesion on red blood cells: mechanism and extended circulation," ExpBiol Med. (Maywood). 232(7), 958-66.
  • Dinh, A-T., Pangarkar, C., and Mitragotri, S., "Understanding intracellular transport processes pertinent to synthetic gene delivery via stochastic simulations and sensitivity analyses," Biophys J., 92(3), 831-46.

2006

  • Karande, P., Jain, A., Arora, A., Ho, M., and Mitragotri, S., "Synergistic Effects of Chemical Enhancers on Skin Permeability: A Case Study of Sodium Lauroylsarcosinate and SorbitanMonolaurate," Eu. J. Pharm. Sci., 31(1), 1-7.
  • Paliwal, S. and Mitragotri, S., "Ultrasound-Induced Cavitation: Applications in Drug and Gene Delivery," Expert Opin Drug Deliv.,3(6), 713-26.
  • Baxter, J. and Mitragotri, S., "Mechanisms of Needle-Free Liquid Injections," Expert Rev. Med. Device, 3(5), 565-74.
  • Karande, P., Jain, A., and Mitragotri, S., "Insights into Synergistic Interactions of Chemical Penetration Enhancers in Binary Mixtures for Transdermal Drug Delivery," J. Control Rel., 115(1), 85-93.
  • Dinh, T., Theofanous, T., and Mitragotri, S., "Theory of Melanosome Transport in Melanophores," J. Theo. Biol., 244(1), 141-53.
  • Champion, J. and Mitragotri, S., "Role of Target Geometry in Phagocytosis," PNAS, 103(13), 4930-4.
  • Lee, P.J., Ahmad, N., Langer, R., Mitragotri, S., and Prasad Shastri, V., "Evaluation of chemical enhancers in the transdermal delivery of lidocaine," Int. J Pharm. 3;308(1-2), 33-9.
  • Dinh, A-T., Pangarkar, C., Theofanous, T., and Mitragotri, S., "Theory of Spatial Patterns of Intracellular Organelles," Biophysical J., 90(10), L67-9.
  • Paliwal, S., Menon, G.K., and Mitragotri, S., "Low Frequency Sonophoresis: Ultrastructural Basis for Stratum Corneum Permeability," J. Invest. Dermatol., 126(5), 1095-101.
  • Karande, P., Jain, A., and Mitragotri, S., "Relationships between Skin’s Electrical Impedance and Permeability in the Presence of Chemical Enhancers," J. Control. Rel., 110(2), 307-13.
  • Mitragotri, S., "Current Status and Future Prospects of Needle-free Liquid Jet Injectors," Nature Reviews Drug Discovery, 5(7), 543-548.

2005

  • Mitragotri, S., "Immunization without Needles," Nature Reviews Immunology, 5(12), 905-16.
  • Baxter, J. and Mitragotri, S., "Jet-Induced Erosion and its impact on Needle-free Jet Injections: Experimental Studies and a Predictive Model," J. Control. Rel., 106(3):361-73.
  • Dinh, A., Theofanous, T., and Mitragotri, S., "A Model for Intracellular Trafficking of Adenoviral Vectors," Biophys. J., 89(3), 1574-88.
  • Pangarkar, C., Dinh, T., and Mitragotri, S., "Dynamics and Spatial Organization of Endosomes in Mammalian Cells," Phys. Rev. Lett., 95, 158101.
  • Newsam, J., Smith, D., Karande, P., Jain, A., Fyigein, E., and Mitragotri, S., "Leveraging High Throughput Experimentation at the Materials-Biology Interface," J. Mater. Chem.5(30), 3061-3068.
  • Karande, P., Jain, A., and Mitragotri, S., "Design Principles of Chemical Penetration Enhancers for Transdermal Drug Delivery," PNAS102(3), 4688-4693.
  • Jain, A., Karande, P., and Mitragotri, S., "Skin Impedance Guided High Throughput Screening of Penetration Enhancers: Methods and Applications," In Percutaneous Absorption, Eds. Bronaugh, R.L. and Maibach, H. I., Marcel Dekker, New York.
  • Mitragotri, S., "Transdermal Drug Delivery  using Low Frequency Sonophoresis," BioMEMS and Biomedical Nanotechnology, 223-236.
  • Jain, A., Karande, P., and Mitragotri, S., "Synergistic Combinations of Penetration Enhancers and their Discovery by High Throughput Screening," In Pharmaceutical Exepients, Eds. Chaubal, M. and Katdare, A. (Eds), 251.
  • Jain, A., Karande, P., and Mitragotri, S., "High Throughput Screening of Chemical Enhancers: Opportunities, Methods, and Applications," In Penetration Enhancers, Smith, E. and Maibach, H., CRC Press, Boca Raton, 155, 851.
  • Whitehead, K. and Mitragotri, S., "Oral Delivery of Macromolecules," In Drug Delivery Companies Report, Winter/Autumn, 2005.
  • Tezel, A., Paliwal, S., Shen, Z., and Mitragotri, S., "Low-Frequency Ultrasound as a Transcutaneous Vaccination Adjuvant," Vaccine, 23(29),3800-7.
  • Paliwal, S., Sundaram, J., and Mitragotri, S., "Induction of Cancer-specific Cytotoxicity  towards Skin and Prostate Cancer Cells using Quercetin and Ultrasound," Br. J. Cancer, 92(3),499-503.
  • Mitragotri, S., "Healing Sound: the Use of Ultrasound in Drug Delivery and other Therapeutic Applications," Nature Reviews Drug Discovery, 4, 255-260.
  • Tezel, A., Dokka, S., Kelley, S., Hardee, G. and Mitragotri, S., "Topical Delivery of Antisense Oligonucleotides using Low-Frequency Ultrasound," Pharm. Res. 12, 2219-2225.

2004

  • Chambers, E. and Mitragotri, S., "Prolonged Circulation of Large Polymeric Nanoparticles by Non-Covalent Adsorption on Erythrocytes," J. Control. Rel, 100(1), 111-9.
  • Mitragotri, S., "Sonophoresis: A Fifty Year Journey," Drug Discovery Today, 9(17), 735-736.
  • Whitehead, K., Shen, Z., and Mitragotri, S., "Oral Delivery of Macromolecules using Intestinal Patches: Applications to Insulin Delivery," J. Control. Rel, 98(1), 37-45.
  • Baxter, J. and Mitragotri, S., "Needle-Free Jet Injections: Dependence of Jet Penetration and Dispersion in the Skin on Jet Power," J. Control. Rel., 97(3), 527-535.
  • Karande, P., Jain, A., and Mitragotri, S., "Discovery of Safe and Potent Transdermal Penetration Enhancers by High Throughput Screening," Nature Biotechnology, 22(3), 192-197.
  • Schramm, J., Katrencik, J., and Mitragotri, S., "Jet Injection into Polyacrylamide Gels: Investigation of Jet Injection Mechanics," J. Biomechanics, 37(8), 1181-1188.
  • Mitragotri, S., "Breaking the Skin Barrier: Technologies for Enhancing Skin Permeability," Adv. Drug Del. Rev., 56(5), 555-556.
  • Prausnitz, M., Mitragotri, S., and Langer, R., "Curent Status and Future Potential of Transdermal Drug Delivery," Nature Reviews Drug Discovery, 3, 115-124.
  • Mitragotri, S. and Kost, J., "Low-Frequency Sonophoresis," Adv. Drug Del. Rev., 56(5), 589-601.
  • Tezel, A. and Mitragotri, S., "Interactions of Cavitation Bubbles with the Stratum Corneum during Low-Frequency Sonophoresis," Biophys. J., 85, 1-11.

2003

  • Lahann, J., Mitragotri, S., Tran, S., Kaido, H., Sundaram, S., Somorjai, G., and Langer, R., "A Reversibly Switching Surface," Science, 299, 371-774.
  • Sundaram, J., Mellein, B., and Mitragotri, S., "An Experimental and Theoretical Analysis of Cell Membrane Permeabilization Induced by Low-Frequency Ultrasound," Biophys. J., 84, 1-15.
  • Tezel, A. and Mitragotri, S., "On the Origin of Size-Dependent Tortuosity of Permeation of Hydrophilic Solutes across Stratum Corneum," J. Control. Rel., 86(1), 183-186.
  • Tezel, A., Sens, A., and Mitragotri, S., "Description of Transdermal Transport of Hydrophilic Solutes during Low-Frequency Sonophoresis Based on a Modified Porous Pathway Model," J. Pharm. Sci., 92(1), 381-393.
  • Mitragotri, S., "Modeling Passive Skin Permeability to Hydrophilic and Hydrophobic Solutes based on Four Permeation Pathways," J. Control. Rel., 86 (1), 69-92.
  • Karande, P. and Mitragotri, S., "Dependence of Skin Permeability on Contact Area," Pharm. Res., 20(2), 254-260.
  • Schramm, J. and Mitragotri, S., "A Fundamental Investigation of Drug Delivery using Jet Injectors: Energetics of Jet Formation and Penetration," Pharm. Res., 19(11),1673-1679.

2002

  • Tezel, A., Sens, A., and Mitragotri, S., "A Theoretical Analysis of Low-Frequency Sonophoresis: Dependence of Transdermal Transport Pathways on Frequency and Energy Density," Pharm. Res. 19(12), 1841-1846.
  • Tezel, A., Sens, A., and Mitragotri, S., "Incorporation of Lipophilic Pathways into the Porous Pathway Model to Describe Transdermal Transport during Low-FrequencySonophoresis," J. Control. Rel., 83(1), 183-188.
  • Karande, P. and Mitragotri, S., "High Throughput Screening of Transdermal Enhancer Formulations," Pharm. Res., 19(5), 655-660.
  • Shen, Z. and Mitragotri, S., "Intestinal Patches for Oral Drug Delivery," Pharm. Res., 19(4), 391-395.
  • Mitragotri, S., "A Theoretical Analysis of Permeation of Small Hydrophobic Solutes across the Skin based on Scaled Particle Theory," J. Pharm. Sci., 91, 754-757.
  • Terahara, T., Mitragotri, S., Kost, J., and Langer, R., "Dependence of Low-Frequency Sonophoresis on Ultrasound Parameters: Distance of the Horn and Intensity," Int. J. Pharm., 235, 35-42.
  • Mitragotri, S. and Kost, J., "Ultrasound-Mediated Transdermal Drug Delivery," Modified-Release Drug Delivery Technology, Rathbone, Hadgraft, Roberts (Eds.), 561-570, chapter 46.
  • Terahara, T., Mitragotri, S., and Langer, R.,  "Porous Resins as a Cavitation Enhancer for Low Frequency Sonophoresis," J. Pharm. Sci., 91, 753-759.
  • Tezel, A., Sens, A., and Mitragotri, S., "Investigations of Role of Cavitation in Low-Frequency Sonophoresis using Acoustic Spectroscopy," J. Pharm. Sci., 91, 444-453.
  • Tezel, A., Sanders, A., Tuscherer, J., and Mitragotri, S., "Frequency-dependence of Sonophoresis," Pharm. Res., 18(12), 1694-1700.
  • Tezel, A., Sens, A., Tuscherer, J., and Mitragotri, S., "Synergistic Effect of Surfactants and Low-Frequency Ultrasound on Skin Permeability," J. Pharm. Sci., 91(1), 91-100.

2001

  • Mitragotri, S. and Kost, J., "Transdermal Delivery of Heparin and Low-Molecular Weight Heparin using Low-Frequency Ultrasound," Pharm. Res., 18, 1022-1027.
  • Mitragotri, S., "Effect of Bilayer Disrupting Agents on Skin Permeability to Low-Molecular Weight Hydrophobic Drugs," Pharm. Res., 18, 1022-1028.
  • Tang, H., Mitragotri, S., Blankschtein, D., and Langer, R., "Theoretical Description of Transdermal Transport of Hydrophilic Permeants: Application to Low-Frequency Sonophoresis," J. Pharm. Sci., 90, 543-566.
  • Kost, J., Mitragotri, S., and Langer, R., "Phonophoresis," Topical Absorption of Dermatological Products, 335-351.

2000

  • Mitragotri, S., "Effect of Therapeutic Ultrasound on Partition and Diffusion Coefficients in the Lipid Bilayers of Stratum Corneum," J. Control. Rel., 71, 23-29.
  • Mitragotri, S., "Synergistic Effect Enhancers on Transdermal Drug Delivery," Pharm. Res., 17(11), 1354-1359.
  • Le, L., Kost, J., and Mitragotri, S., "Combined Effect of Low-Frequency Ultrasound and Iontophoresis: Applications for Transdermal Heparin Delivery," Pharm. Res., 17, 1354-1557.
  • Mitragotri, S., "In Situ Determination of Partition and Diffusion Coefficients in the Lipid Bilayers of the Stratum Corneum," Pharm. Res., 17(8), 1024-1027.
  • Mitragotri, S., Kost, J., and Langer, R., "Non-Invasive Drug Delivery and Diagnostics Using Low-Frequency Sonophoresis," Recent Advances and Research Updates, 1, 41-48.
  • Mitragotri, S. and Kost, J., "Low-Frequency Sonophoresis: A non-Invasive Method for Drug Delivery and Diagnostics," Biotechnology Progress, 16(3), 488-492.
  • Mitragotri, S., Coleman, M., Kost, J., and Langer, R., "Analysis of Ultrasonically Extracted Interstitial Fluid as a Predictor of Blood Glucose Levels," J. Appl. Physiol., 89, 961-966.
  • Mitragotri, S., Coleman, M., Kost, J., and Langer, R., "Transdermal Extraction of Analytes using Low-Frequency Ultrasound," Pharm. Res., 17(4), 467-470.
  • Mitragotri, S., Ray, D., Farrell, J., Tang, H., Yu, B., Kost, J., Blankschtein, D., and Langer, R., "Synergistic Effect of Low-Frequency Ultrasound and Sodium Lauryl Sulfate on Transdermal Transport," J. Pharm. Sci., 89, 892-900.
  • Mitragotri, S., Farrell, J., Tang, H., Terahara, T., Kost, J., and Langer, R., "Determination of the Threshold Energy Dose for Ultrasound-Induced Transdermal Drug Delivery," J. Control Rel., 63, 41-52.
  • Kost, J., Mitragotri, S., Gabbay, B., Pishko, M., and Langer, R., "Transdermal Monitoring of Glucose and Other Analytes Using Ultrasound," Nature Med., 6, 347-350.
  • Mitragotri, S., Kost, J., and Langer, R., "Enhancement of Transdermal Transport Using Ultrasound in Combination with Other Enhancers," Handbook of Pharmaceutical Controlled Release Technology, Wise, D. (Ed.), pp. 607-616.
  • Tang, H., Mitragotri, S., Blankschtein, D., and Langer, R., "Enhancement of Transdermal Drug Transport by Ultrasound: Sonophoresis," Encl. of Pharm. Tech., Swarbrick, J., Boylan, J.

Before 2000

  • Mitragotri, S., Johnson, M., Blankschtein, D., and Langer, R., "An Analysis of the Size Selectivity of Solute Partitioning, Diffusion, and Permeation across Lipid Bilayer Systems," Biophys. J., 77, 1268-1283, 1999.
  • Mitragotri, S., Blankschtein, D., and Langer, R., "An Explanation for the Variation of the Sonophoretic Transdermal Transport Enhancement from Drug to Drug," J. Pharm. Sci., 86(10), 1190-92, 1997.
  • Mitragotri, S., Langer, R., and Kost, J., "Ultrasound for Modulation of Skin Transport Properties, Biomaterials Engineering and Devices: Human Applications", Wise, D. (Ed.), pages 843-854, 1999.
  • Constantino, R., Liauw, S., Mitragotri, S., Klibanov, A., Langer, R., and Sluzky, V., "Pharmaceutical Developments of Insulin", In Therapeutic Protein and Peptide Formulation and Delivery, ACS Symposium, Shahrokh, Z., Sluzky, V., Cleland, J., Shrine, S., Randolph, T. (Eds.), 29-66, 1997.
  • Kost, J., Mitragotri, S., and Langer, R., "Phonophoresis, Percutaneous Absorption," In Bronaugh, R., Maibach, H.I., (Eds.), pp. 615-631, 1999.
  • Johnson, M.E., Mitragotri, S., Patel, A., Blankschtein, D., and Langer, R., "Synergistic Effects of Chemical Enhancers and Therapeutic Ultrasound on Transdermal Drug Delivery," J. Pharm. Sci., 85(7), 670-679, 1996.
  • Mitragotri, S., Blankschtein, D., and Langer, R., "Transdermal Drug Delivery Using Low-Frequency Sonophoresis," Pharm. Res., 13(3), 411-420, 1996.
  • Kost, J., Pliquett, U., Mitragotri, S., Yamamoto, A., Langer, R., and Weaver, J., "Synergistic Effect of Electric Field and Ultrasound on Transdermal Transport," Pharm. Res., 13(4), 633-638, 1996.
  • Mitragotri, S., Edwards, D., Blankschtein, D., and Langer, R., "A Mechanistic Study of Ultrasonically-Enhanced Transdermal Drug Delivery," J. Pharm. Sci., 84, 697-706, 1995.
  • Mitragotri, S., Blankschtein, D., and Langer, R., "Sonophoresis: Enhanced Transdermal Drug Delivery by Application of Ultrasound," Encl. of Pharm. Tech., vol. 14, Swarbrick, J., Boylan, J., (Eds.), vol. 14, 103-122, 1996.
  • Mitragotri, S., Blankschtein, D., and Langer, R., "Ultrasound-Mediated Transdermal Protein Delivery," Science, 269, 850-853, 1995.